5ijn: Difference between revisions

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{{Large structure}}
 
==Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205)==
==Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205)==
<StructureSection load='5ijn' size='340' side='right' caption='[[5ijn]], [[Resolution|resolution]] 21.40&Aring;' scene=''>
<SX load='5ijn' size='340' side='right' viewer='molstar' caption='[[5ijn]], [[Resolution|resolution]] 21.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ijn]] is a 26 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IJN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ijn]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IJN FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ijn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ijn OCA], [http://pdbe.org/5ijn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ijn RCSB], [http://www.ebi.ac.uk/pdbsum/5ijn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ijn ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 21.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ijn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ijn OCA], [https://pdbe.org/5ijn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ijn RCSB], [https://www.ebi.ac.uk/pdbsum/5ijn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ijn ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/NUP62_HUMAN NUP62_HUMAN]] Familial infantile bilateral striatal necrosis. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN]] Familial atrial fibrillation. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN] Familial atrial fibrillation. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NUP62_HUMAN NUP62_HUMAN]] Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex. [[http://www.uniprot.org/uniprot/NUP54_HUMAN NUP54_HUMAN]] Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. [[http://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN]] Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.[UniProtKB:Q99P88] [[http://www.uniprot.org/uniprot/NU205_HUMAN NU205_HUMAN]] Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC.<ref>PMID:15229283</ref>  [[http://www.uniprot.org/uniprot/NUP93_HUMAN NUP93_HUMAN]] Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.<ref>PMID:15229283</ref> <ref>PMID:15703211</ref>  [[http://www.uniprot.org/uniprot/NUP58_HUMAN NUP58_HUMAN]] Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
[https://www.uniprot.org/uniprot/NU155_HUMAN NU155_HUMAN] Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.[UniProtKB:Q99P88]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ijn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ijn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Appen, A von]]
[[Category: Homo sapiens]]
[[Category: Beck, M]]
[[Category: Large Structures]]
[[Category: Kosinski, J]]
[[Category: Beck M]]
[[Category: Mosalaganti, S]]
[[Category: Kosinski J]]
[[Category: Nuclear pore complex]]
[[Category: Mosalaganti S]]
[[Category: Nucleocytoplasmic transport]]
[[Category: Von Appen A]]
[[Category: Transport protein]]

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