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[[Image:1vtm.gif|left|200px]]


{{Structure
==STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION==
|PDB= 1vtm |SIZE=350|CAPTION= <scene name='initialview01'>1vtm</scene>, resolution 3.5&Aring;
<StructureSection load='1vtm' size='340' side='right'caption='[[1vtm]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
<table><tr><td colspan='2'>[[1vtm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tobacco_mild_green_mosaic_virus Tobacco mild green mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTM FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Fiber diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtm OCA], [https://pdbe.org/1vtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vtm RCSB], [https://www.ebi.ac.uk/pdbsum/1vtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vtm ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtm OCA], [http://www.ebi.ac.uk/pdbsum/1vtm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vtm RCSB]</span>
[https://www.uniprot.org/uniprot/CAPSD_TMGMV CAPSD_TMGMV] Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vt/1vtm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vtm ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION'''
==See Also==
 
*[[Tobacco Mosaic Virus|Tobacco Mosaic Virus]]
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
==Overview==
__TOC__
The structure of the U2 strain of tobacco mosaic virus (TMV) has been determined by fiber diffraction methods at 3.5 A resolution, and refined by a combination of restrained least-squares and molecular dynamics methods to an R-factor of 0.096. The structure is extremely similar to that of the common strain of TMV, with the largest differences being in the protein loop that makes up the inner surface of the virus, and in the C-terminal region on the outer surface. Differences in the inner loop can be correlated with differences in the properties of the two viruses.
</StructureSection>
 
[[Category: Large Structures]]
==About this Structure==
[[Category: Tobacco mild green mosaic virus]]
1VTM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTM OCA].
[[Category: Pattanayek R]]
 
[[Category: Stubbs G]]
==Reference==
Structure of the U2 strain of tobacco mosaic virus refined at 3.5 A resolution using X-ray fiber diffraction., Pattanayek R, Stubbs G, J Mol Biol. 1992 Nov 20;228(2):516-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1453461 1453461]
[[Category: Single protein]]
[[Category: Pattanayek, R.]]
[[Category: Stubbs, G.]]
[[Category: icosahedral virus]]
[[Category: virus]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:28:17 2008''

Latest revision as of 11:47, 14 February 2024

STRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTIONSTRUCTURE OF THE U2 STRAIN OF TOBACCO MOSAIC VIRUS REFINED AT 3.5 ANGSTROMS RESOLUTION USING X-RAY FIBER DIFFRACTION

Structural highlights

1vtm is a 2 chain structure with sequence from Tobacco mild green mosaic virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Fiber diffraction, Resolution 3.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAPSD_TMGMV Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1vtm, resolution 3.50Å

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