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==STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION==
==STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION==
<StructureSection load='5vmq' size='340' side='right' caption='[[5vmq]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
<StructureSection load='5vmq' size='340' side='right'caption='[[5vmq]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5vmq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VMQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VMQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5vmq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_S88 Escherichia coli S88]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gq3 1gq3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VMQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.012&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_carbamoyltransferase Aspartate carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.2 2.1.3.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vmq OCA], [http://pdbe.org/5vmq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vmq RCSB], [http://www.ebi.ac.uk/pdbsum/5vmq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vmq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vmq OCA], [https://pdbe.org/5vmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vmq RCSB], [https://www.ebi.ac.uk/pdbsum/5vmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vmq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRB_ECO45 PYRB_ECO45]
==See Also==
*[[Aspartate carbamoyltransferase 3D structures|Aspartate carbamoyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspartate carbamoyltransferase]]
[[Category: Escherichia coli S88]]
[[Category: Beernink, P T]]
[[Category: Large Structures]]
[[Category: Endrizzi, J A]]
[[Category: Beernink PT]]
[[Category: Mutant]]
[[Category: Endrizzi JA]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Rossmann fold]]
[[Category: Transferase]]

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