1v4n: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1v4n.gif|left|200px]]


{{Structure
==Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii==
|PDB= 1v4n |SIZE=350|CAPTION= <scene name='initialview01'>1v4n</scene>, resolution 2.45&Aring;
<StructureSection load='1v4n' size='340' side='right'caption='[[1v4n]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1v4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V4N FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/S-methyl-5-thioadenosine_phosphorylase S-methyl-5-thioadenosine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.28 2.4.2.28] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
|GENE= ST0485 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 Sulfolobus tokodaii])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4n OCA], [https://pdbe.org/1v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v4n RCSB], [https://www.ebi.ac.uk/pdbsum/1v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v4n ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4n OCA], [http://www.ebi.ac.uk/pdbsum/1v4n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v4n RCSB]</span>
[https://www.uniprot.org/uniprot/F9VN03_SULTO F9VN03_SULTO] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/1v4n_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
1V4N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4N OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: S-methyl-5-thioadenosine phosphorylase]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v4n ConSurf].
[[Category: Sulfolobus tokodaii]]
<div style="clear:both"></div>
[[Category: Kawarabayasi, Y.]]
__TOC__
[[Category: Kitago, Y.]]
</StructureSection>
[[Category: Sakai, N.]]
[[Category: Large Structures]]
[[Category: Tanaka, I.]]
[[Category: Sulfurisphaera tokodaii]]
[[Category: Tsujimura, M.]]
[[Category: Kawarabayasi Y]]
[[Category: Watanabe, N.]]
[[Category: Kitago Y]]
[[Category: Yao, M.]]
[[Category: Sakai N]]
[[Category: Yasutake, Y.]]
[[Category: Tanaka I]]
[[Category: structural genomic]]
[[Category: Tsujimura M]]
[[Category: transferase]]
[[Category: Watanabe N]]
 
[[Category: Yao M]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:19:22 2008''
[[Category: Yasutake Y]]

Latest revision as of 03:35, 21 November 2024

Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaiiStructure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii

Structural highlights

1v4n is a 3 chain structure with sequence from Sulfurisphaera tokodaii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.45Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

F9VN03_SULTO Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1v4n, resolution 2.45Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1v4n&oldid=4203248"