4z7g: Difference between revisions

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OCA

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 ==Crystal structure of human IRE1 cytoplasmic kinase-RNase region - apo==
-<StructureSection load='4z7g' size='340' side='right' caption='[[4z7g]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+<StructureSection load='4z7g' size='340' side='right'caption='[[4z7g]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4z7g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z7G FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4z7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z7G FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z7g OCA], [http://pdbe.org/4z7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z7g RCSB], [http://www.ebi.ac.uk/pdbsum/4z7g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z7g ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z7g OCA], [https://pdbe.org/4z7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z7g RCSB], [https://www.ebi.ac.uk/pdbsum/4z7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z7g ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ERN1_HUMAN ERN1_HUMAN]] Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.<ref>PMID:9637683</ref> <ref>PMID:11175748</ref> <ref>PMID:12637535</ref> [UniProtKB:Q9EQY0]
+[https://www.uniprot.org/uniprot/ERN1_HUMAN ERN1_HUMAN] Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.<ref>PMID:9637683</ref> <ref>PMID:11175748</ref> <ref>PMID:12637535</ref> [UniProtKB:Q9EQY0]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 19: @@
 </div>
 <div class="pdbe-citations 4z7g" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Ire1|Ire1]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bayliss, R]]
+[[Category: Homo sapiens]]
-[[Category: Joshi, A]]
+[[Category: Large Structures]]
-[[Category: Kinase]]
+[[Category: Bayliss R]]
-[[Category: Rnase]]
+[[Category: Joshi A]]
-[[Category: Transferase]]
-[[Category: Unfolded protein response]]