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==M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE==
==M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE==
<StructureSection load='1bvr' size='340' side='right' caption='[[1bvr]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1bvr' size='340' side='right'caption='[[1bvr]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1bvr]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BVR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1bvr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BVR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=THT:TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER'>THT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=THT:TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER'>THT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bvr OCA], [http://pdbe.org/1bvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bvr RCSB], [http://www.ebi.ac.uk/pdbsum/1bvr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bvr ProSAT], [http://www.topsan.org/Proteins/TBSGC/1bvr TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bvr OCA], [https://pdbe.org/1bvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bvr RCSB], [https://www.ebi.ac.uk/pdbsum/1bvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bvr ProSAT], [https://www.topsan.org/Proteins/TBSGC/1bvr TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/1bvr_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/1bvr_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
*[[Mannose-binding protein|Mannose-binding protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bittman, R]]
[[Category: Large Structures]]
[[Category: Jacobs, W]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Rozwarski, D A]]
[[Category: Bittman R]]
[[Category: Sugantino, M]]
[[Category: Jacobs W]]
[[Category: Structural genomic]]
[[Category: Rozwarski DA]]
[[Category: Vilcheze, C]]
[[Category: Sugantino M]]
[[Category: Nadh-dependent enoyl-acp reductase]]
[[Category: Vilcheze C]]
[[Category: Oxidoreductase]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tbsgc]]

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