4z1i: Difference between revisions

<StructureSection load='4z1i' size='340' side='right'caption='[[4z1i]], [[Resolution|resolution]] 3.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[4z1i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z1I FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z1i OCA], [https://pdbe.org/4z1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z1i RCSB], [https://www.ebi.ac.uk/pdbsum/4z1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z1i ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TRAP1_HUMAN TRAP1_HUMAN] Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.<ref>PMID:23525905</ref> <ref>PMID:23564345</ref> <ref>PMID:23747254</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Kang BH]]

[[Category: Lee C]]

[[Category: Park HK]]

[[Category: Ryu JH]]