4u63: Difference between revisions

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==Crystal structure of a bacterial class III photolyase from Agrobacterium tumefaciens at 1.67A resolution==
==Crystal structure of a bacterial class III photolyase from Agrobacterium tumefaciens at 1.67A resolution==
<StructureSection load='4u63' size='340' side='right' caption='[[4u63]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
<StructureSection load='4u63' size='340' side='right'caption='[[4u63]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4u63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U63 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4u63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U63 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MHF:5,10-METHENYL-6,7,8-TRIHYDROFOLIC+ACID'>MHF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u63 OCA], [http://pdbe.org/4u63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u63 RCSB], [http://www.ebi.ac.uk/pdbsum/4u63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u63 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MHF:5,10-METHENYL-6,7,8-TRIHYDROFOLIC+ACID'>MHF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u63 OCA], [https://pdbe.org/4u63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u63 RCSB], [https://www.ebi.ac.uk/pdbsum/4u63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u63 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PHRA_AGRT5 PHRA_AGRT5]] Photolyase involved in the repair of UV radiation-induced DNA damage. By using blue-light energy, catalyzes the photoreactivation of cyclobutane pyrimidine dimers (CPDs), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Can repair CPD lesions in ssDNA as well as in dsDNA.<ref>PMID:22066008</ref>
[https://www.uniprot.org/uniprot/PHRA_AGRFC PHRA_AGRFC] Photolyase involved in the repair of UV radiation-induced DNA damage. By using blue-light energy, catalyzes the photoreactivation of cyclobutane pyrimidine dimers (CPDs), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Can repair CPD lesions in ssDNA as well as in dsDNA.<ref>PMID:22066008</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kalms, J]]
[[Category: Agrobacterium fabrum str. C58]]
[[Category: Krauss, N]]
[[Category: Large Structures]]
[[Category: Lamparter, T]]
[[Category: Kalms J]]
[[Category: Oberpichler, I]]
[[Category: Krauss N]]
[[Category: Scheerer, P]]
[[Category: Lamparter T]]
[[Category: Stetten, D von]]
[[Category: Oberpichler I]]
[[Category: Zhang, F]]
[[Category: Scheerer P]]
[[Category: Agrobacterium tumefacien]]
[[Category: Zhang F]]
[[Category: Cyclopyrimidine dimer]]
[[Category: Von Stetten D]]
[[Category: Dna]]
[[Category: Dna damage]]
[[Category: Dna repair]]
[[Category: Double-stranded]]
[[Category: Fad]]
[[Category: Flavin]]
[[Category: Flavoprotein]]
[[Category: Lyase]]
[[Category: Methenyltetrahydrofolate]]
[[Category: Photolyase]]
[[Category: Photoreduction]]
[[Category: Trp triade]]
[[Category: Ultraviolet ray]]

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