5us7: Difference between revisions
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New page: '''Unreleased structure''' The entry 5us7 is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Human bocavirus 3== | |||
<SX load='5us7' size='340' side='right' viewer='molstar' caption='[[5us7]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5us7]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_bocavirus_3 Human bocavirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5US7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5us7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us7 OCA], [https://pdbe.org/5us7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5us7 RCSB], [https://www.ebi.ac.uk/pdbsum/5us7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5us7 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAPSD_HBOC3 CAPSD_HBOC3] Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA (By similarity). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).[UniProtKB:Q3YPH4][UniProtKB:Q9PZT0] | |||
__TOC__ | |||
</SX> | |||
[[Category: Human bocavirus 3]] | |||
[[Category: Large Structures]] | |||
[[Category: Agbandje-McKenna M]] | |||
[[Category: Mietzsch M]] | |||
Latest revision as of 17:09, 13 March 2024
Human bocavirus 3Human bocavirus 3
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