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==E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine== | |||
<StructureSection load='5knr' size='340' side='right'caption='[[5knr]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5knr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.864Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [https://pdbe.org/5knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [https://www.ebi.ac.uk/pdbsum/5knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine. | |||
==See Also== | |||
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Eng | [[Category: Large Structures]] | ||
[[Category: | [[Category: Eng WS]] | ||
[[Category: Janeba | [[Category: Hockova D]] | ||
[[Category: Janeba Z]] | |||
[[Category: Keough DT]] | |||
Latest revision as of 13:04, 27 September 2023
E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanineE. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine
Structural highlights
FunctionHPRT_ECOLI Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine. See Also |
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