5mae: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==CATHEPSIN L IN COMPLEX WITH (2S,4R)-4-(2-Chloro-4-methoxy-benzenesulfonyl)-1-[3-(5-chloro-pyridin-2-yl)-azetidine-3-carbonyl]-pyrrolidine-2-car boxylic acid (1-cyano-cyclopropyl)-amide==
-<StructureSection load='5mae' size='340' side='right' caption='[[5mae]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
+<StructureSection load='5mae' size='340' side='right'caption='[[5mae]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5mae]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MAE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MAE FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5mae]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MAE FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7KN:[4-[CYCLOPENTYL(PYRAZIN-2-YLMETHYL)AMINO]-6-MORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL]METHYLIDENEAZANIDE'>7KN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7KN:[4-[CYCLOPENTYL(PYRAZIN-2-YLMETHYL)AMINO]-6-MORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL]METHYLIDENEAZANIDE'>7KN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mae OCA], [http://pdbe.org/5mae PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mae RCSB], [http://www.ebi.ac.uk/pdbsum/5mae PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mae ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mae OCA], [https://pdbe.org/5mae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mae RCSB], [https://www.ebi.ac.uk/pdbsum/5mae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mae ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN]] Important for the overall degradation of proteins in lysosomes.
+[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 19: / Line 19: @@
 </div>
 <div class="pdbe-citations 5mae" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Cathepsin 3D structures|Cathepsin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Cathepsin L]]
+[[Category: Homo sapiens]]
-[[Category: Benz, J]]
+[[Category: Large Structures]]
-[[Category: Kuglstatter, A]]
+[[Category: Benz J]]
-[[Category: Stihle, M]]
+[[Category: Kuglstatter A]]
-[[Category: Hydrolase]]
+[[Category: Stihle M]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Protease inhibitor]]