4bw5: Difference between revisions
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==Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1)== | ==Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1)== | ||
<StructureSection load='4bw5' size='340' side='right' caption='[[4bw5]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='4bw5' size='340' side='right'caption='[[4bw5]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bw5]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4bw5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BW5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bw5 OCA], [https://pdbe.org/4bw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bw5 RCSB], [https://www.ebi.ac.uk/pdbsum/4bw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bw5 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/KCNKA_HUMAN KCNKA_HUMAN] Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Potassium | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Bountra | [[Category: Arrowsmith CH]] | ||
[[Category: Burgess-Brown | [[Category: Bountra C]] | ||
[[Category: Carpenter | [[Category: Burgess-Brown N]] | ||
[[Category: Carpenter EP]] | |||
[[Category: Dong | [[Category: Dong L]] | ||
[[Category: Dong | [[Category: Dong YY]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Goubin | [[Category: Goubin S]] | ||
[[Category: Grieben | [[Category: Grieben M]] | ||
[[Category: Mackenzie | [[Category: Mackenzie A]] | ||
[[Category: Mukhopadhyay | [[Category: Mukhopadhyay S]] | ||
[[Category: Pike | [[Category: Pike ACW]] | ||
[[Category: Quigley | [[Category: Quigley A]] | ||
[[Category: Shintre | [[Category: Shintre CA]] | ||
[[Category: Shrestha | [[Category: Shrestha L]] | ||
[[Category: Strain-Damerell | [[Category: Strain-Damerell C]] | ||
[[Category: Vollmar | [[Category: Vollmar M]] | ||
[[Category: | [[Category: Von Delft F]] | ||