4jz1: Difference between revisions

<StructureSection load='4jz1' size='340' side='right'caption='[[4jz1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>

<table><tr><td colspan='2'>[[4jz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JZ1 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F4D:4,4-[(3-{[(4-FLUOROPHENYL)SULFONYL]AMINO}PYRIDINE-2,6-DIYL)BIS(OXY)]DIBENZENECARBOXIMIDAMIDE'>F4D</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jz1 OCA], [https://pdbe.org/4jz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jz1 RCSB], [https://www.ebi.ac.uk/pdbsum/4jz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jz1 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN] Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:[https://omim.org/entry/610765 610765]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.<ref>PMID:17273967</ref>  

[https://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN] Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.

*[[Matriptase 3D structures|Matriptase 3D structures]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Ashok KN]]

[[Category: Chakshusmathi G]]

[[Category: Ramesh KS]]

[[Category: Ravi BC]]

[[Category: Subramanya HS]]