4ass: Difference between revisions

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 ==TubR bound to tubC - 26 bp - from Bacillus thuringiensis serovar israelensis pBtoxis==
-<StructureSection load='4ass' size='340' side='right' caption='[[4ass]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
+<StructureSection load='4ass' size='340' side='right'caption='[[4ass]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ass]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._thuringiensis"_smith_et_al._1952 "bacillus cereus var. thuringiensis" smith et al. 1952]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ASS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ass]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ASS FirstGlance]. <br>
-</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 7&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4asn|4asn]], [[4aso|4aso]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ass FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ass OCA], [http://pdbe.org/4ass PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ass RCSB], [http://www.ebi.ac.uk/pdbsum/4ass PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ass ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ass FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ass OCA], [https://pdbe.org/4ass PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ass RCSB], [https://www.ebi.ac.uk/pdbsum/4ass PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ass ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/TUBR_BACTI TUBR_BACTI] A DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBtoxis plasmid. Cooperatively binds to the centromere-like site (tubC), which may seed filament formation by the TubZ polymerizing GTPase, stabilizing TubZ filaments. TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling plasmid within the cell (PubMed:20534443, PubMed:23010931, PubMed:25825718). Required for plasmid replication (PubMed:16936050, PubMed:17873046). Negatively regulates levels of TubZ; its effect on RNA expression has not been shown (Probable). Specifically binds iterons, 12-bp imperfect direct repeats that function as a plasmid origin of replication (PubMed:17873046, PubMed:23010931, PubMed:25825718). Four TubR dimers bind to tubC, forming an extended bent DNA-protein filament with protein wrapping helically around the outside of the DNA (PubMed:20534443, PubMed:23010931).<ref>PMID:16936050</ref> <ref>PMID:17873046</ref> <ref>PMID:20534443</ref> <ref>PMID:23010931</ref> <ref>PMID:25825718</ref> <ref>PMID:17510284</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 23: @@
 __TOC__
 </StructureSection>
-[[Category: Bacillus cereus var. thuringiensis smith et al. 1952]]
+[[Category: Bacillus thuringiensis]]
-[[Category: Aylett, C H.S]]
+[[Category: Large Structures]]
-[[Category: Lowe, J]]
+[[Category: Aylett CHS]]
-[[Category: Partitioning]]
+[[Category: Lowe J]]
-[[Category: Segregation]]
-[[Category: Structural protein-dna complex]]