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==Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491== | |||
<StructureSection load='5svr' size='340' side='right'caption='[[5svr]], [[Resolution|resolution]] 3.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5svr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SVR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.13Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=71C:5-{[(3-PHENOXYPHENYL)METHYL][(1S)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL]CARBAMOYL}BENZENE-1,2,4-TRICARBOXYLIC+ACID'>71C</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5svr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5svr OCA], [https://pdbe.org/5svr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5svr RCSB], [https://www.ebi.ac.uk/pdbsum/5svr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5svr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/P2RX3_HUMAN P2RX3_HUMAN] Receptor for ATP that acts as a ligand-gated ion channel. | |||
==See Also== | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gouaux E]] | |||
[[Category: Lu W]] | |||
[[Category: Mansoor SE]] | |||
[[Category: Oosterheert W]] | |||
[[Category: Shekhar M]] | |||
[[Category: Tajkhorshid E]] | |||
Latest revision as of 18:33, 6 March 2024
Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491
Structural highlights
FunctionP2RX3_HUMAN Receptor for ATP that acts as a ligand-gated ion channel. See Also |
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