5tb4: Difference between revisions

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New page: '''Unreleased structure''' The entry 5tb4 is ON HOLD Authors: Clarke, O.B., des Georges, A., Zalk, R., Marks, A.R., Hendrickson, W.A., Frank, J. Description: Structural basis for gatin...
 
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'''Unreleased structure'''


The entry 5tb4 is ON HOLD
==Structure of rabbit RyR1 (EGTA-only dataset, class 4)==
 
<SX load='5tb4' size='340' side='right' viewer='molstar' caption='[[5tb4]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
Authors: Clarke, O.B., des Georges, A., Zalk, R., Marks, A.R., Hendrickson, W.A., Frank, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5tb4]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TB4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TB4 FirstGlance]. <br>
Description: Structural basis for gating and activation of RyR1 (30 uM Ca2+ dataset, all particles)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Zalk, R]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tb4 OCA], [https://pdbe.org/5tb4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tb4 RCSB], [https://www.ebi.ac.uk/pdbsum/5tb4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tb4 ProSAT]</span></td></tr>
[[Category: Marks, A.R]]
</table>
[[Category: Des Georges, A]]
== Function ==
[[Category: Frank, J]]
[https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
[[Category: Clarke, O.B]]
__TOC__
[[Category: Hendrickson, W.A]]
</SX>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Clarke OB]]
[[Category: Frank J]]
[[Category: Hendrickson WA]]
[[Category: Marks AR]]
[[Category: Zalk R]]
[[Category: Des Georges A]]

Latest revision as of 18:39, 6 March 2024

Structure of rabbit RyR1 (EGTA-only dataset, class 4)Structure of rabbit RyR1 (EGTA-only dataset, class 4)

5tb4, resolution 4.50Å

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