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==Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAM==
==Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAM==
<StructureSection load='5hg0' size='340' side='right' caption='[[5hg0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='5hg0' size='340' side='right'caption='[[5hg0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hg0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HG0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hg0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_SCHU_S4 Francisella tularensis subsp. tularensis SCHU S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HG0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hg0 OCA], [https://pdbe.org/5hg0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hg0 RCSB], [https://www.ebi.ac.uk/pdbsum/5hg0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hg0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hg0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hg0 OCA], [http://pdbe.org/5hg0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hg0 RCSB], [http://www.ebi.ac.uk/pdbsum/5hg0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hg0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PANC_FRATT PANC_FRATT]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).  
[https://www.uniprot.org/uniprot/PANC_FRATT PANC_FRATT] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).
 
==See Also==
*[[Pantothenate synthetase|Pantothenate synthetase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Francisella tularensis subsp. tularensis SCHU S4]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Chang, C]]
[[Category: Chang C]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Kim, Y]]
[[Category: Kim Y]]
[[Category: Maltseva, N]]
[[Category: Maltseva N]]
[[Category: Papazisi, L]]
[[Category: Papazisi L]]
[[Category: Csgid]]
[[Category: Ligase]]
[[Category: Pantoate-beta-alanine ligase]]
[[Category: Sructural genomic]]

Latest revision as of 10:34, 9 August 2023

Crystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAMCrystal Structure of Pantoate-beta-alanine Ligase from Francisella tularensis complex with SAM

Structural highlights

5hg0 is a 2 chain structure with sequence from Francisella tularensis subsp. tularensis SCHU S4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PANC_FRATT Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity).

See Also

5hg0, resolution 2.40Å

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