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| <StructureSection load='1eej' size='340' side='right' caption='E. coli DsbC complex with MES (PDB code [[1eej]])' scene=''> | | <StructureSection load='' size='340' side='right' caption='E. coli DsbC complex with MES (PDB code [[1eej]])' scene='70/705687/Cv/1'> |
| | __TOC__ |
| == Function == | | == Function == |
| '''Thiol:disulfide interchange protein''' is a prokaryotic disulfide bond isomerase. <br /> | | '''Thiol:disulfide interchange protein''' is a prokaryotic disulfide bond isomerase. <br /> |
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| == Structural highlights == | | == Structural highlights == |
| DsbC active site contains a CXXC motif which modulates the disulfide isomerization and protein folding in the bacterial periplasmic space<ref>PMID:11208797</ref>. | | DsbC active site contains a <scene name='70/705687/Cv/2'>CXXC motif</scene> which modulates the disulfide isomerization and protein folding in the bacterial periplasmic space<ref>PMID:11208797</ref><ref>PMID:11208797</ref>. |
| </StructureSection> | |
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| == 3D Structures of thiol:disulfide interchange protein == | | == 3D Structures of thiol:disulfide interchange protein == |
| | [[Thiol:disulfide interchange protein 3D structures]] |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | </StructureSection> |
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *Thiol:disulfide interchange protein (DsbC)
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| **[[1eej]], [[1tjd]] – EcDsbC – ''Escherichal coli'' <BR />
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| **[[1g0t]], [[1jzo]] – EcDsbC (mutant) <BR />
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| **[[2iyj]] – EcDsbC N terminal<BR />
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| **[[1jzd]] – EcDsbC (mutant) + DsbD N terminal<BR />
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| **[[1t3b]] – DsbC – ''Haemophilus influenzae'' <BR />
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| **[[4fyb]], [[4fyc]] – HpDsbC – ''Helicobacter pylori'' <BR />
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| **[[4i5q]] – StDsbC – ''Salmonella typhimurium''<BR />
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| **[[4ilf]] – StDsbC (mutant) <BR />
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| **[[4npb]] – DsbC –'' Yersinia pestis'' <BR />
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| *Thiol:disulfide interchange protein (DsbD)
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| **[[1l6p]], [[1jpe]], [[3pfu]] – EcDsbD N terminal<BR />
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| **[[1uc7]], [[2fwe]], [[2fwf]] [[2fwg]], [[2fwh]] – EcDsbD C terminal<BR />
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| **[[4ip1]], [[4ip6]] – EcDsbD C terminal (mutant)<BR />
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| **[[1vrs]] – EcDsbD N terminal (mutant) + C terminal (mutant)<BR />
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| **[[1z5y]] – EcDsbD N terminal (mutant) + EcDsbE soluble domain (mutant)<BR />
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| **[[2k0r]] – NmDsbD N terminal – ''Neisseria meningitis''<BR />
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| **[[2k9f]] – NmDsbD N terminal + thoredoxin<BR />
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| *Thiol:disulfide interchange protein (DsbE)
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| **[[2b1k]], [[3k8n]] – EcDsbE <BR />
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| **[[2b1l]], [[2g0f]] – EcDsbE (mutant) <BR />
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| **[[3kh7]], [[3kh9]] – DsbE soluble domain – ''Pseudomonas aeruginosa''<BR />
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| *Thiol:disulfide interchange protein (DsbG)
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| **[[1v57]], [[1v58]] – EcDsbG <BR />
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| **[[2h0g]], [[2h0h]], [[2h0i]], [[5g1k]], [[5g1l] – EcDsbG (mutant) <BR />
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| **[[2iy2]] – EcDsbG N terminal<BR />
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| **[[4ihu]] – MtDsbG <BR />
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| **[[3tdg]] – HpDsbG<BR />
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| *Thiol:disulfide interchange protein (DsbP)
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| **[[4ml1]], [[4ml6]], [[4mly]] – DsbP – ''Klebsiella pneumoniae'' <BR />
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| | [[Category:Topic Page]] |