5jo0: Difference between revisions

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 ==Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC56 and manganese==
-<StructureSection load='5jo0' size='340' side='right' caption='[[5jo0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='5jo0' size='340' side='right'caption='[[5jo0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5jo0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JO0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5jo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JO0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LR:MORPHOLINE'>6LR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L56:[(2R)-2-{2-[HYDROXY(METHYL)AMINO]-2-OXOETHYL}-5-(3-METHYLPHENYL)PENTYL]PHOSPHONIC+ACID'>L56</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-deoxy-D-xylulose-5-phosphate_reductoisomerase 1-deoxy-D-xylulose-5-phosphate reductoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.267 1.1.1.267] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6LR:MORPHOLINE'>6LR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=L56:[(2R)-2-{2-[HYDROXY(METHYL)AMINO]-2-OXOETHYL}-5-(3-METHYLPHENYL)PENTYL]PHOSPHONIC+ACID'>L56</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jo0 OCA], [http://pdbe.org/5jo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jo0 RCSB], [http://www.ebi.ac.uk/pdbsum/5jo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jo0 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jo0 OCA], [https://pdbe.org/5jo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jo0 RCSB], [https://www.ebi.ac.uk/pdbsum/5jo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jo0 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/DXR_PLAF7 DXR_PLAF7]] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
+[https://www.uniprot.org/uniprot/DXR_PLAF7 DXR_PLAF7] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 </div>
 <div class="pdbe-citations 5jo0" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
+[[Category: Large Structures]]
-[[Category: Bergfors, T]]
+[[Category: Plasmodium falciparum 3D7]]
-[[Category: Jones, T A]]
+[[Category: Bergfors T]]
-[[Category: Mowbray, S L]]
+[[Category: Jones TA]]
-[[Category: Sooriyaarachchi, S]]
+[[Category: Mowbray SL]]
-[[Category: Enzyme-inhibitor complex]]
+[[Category: Sooriyaarachchi S]]
-[[Category: Isoprenoid biosynthesis]]
-[[Category: Mep pathway]]
-[[Category: Oxidoreductase]]