4j2q: Difference between revisions
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==Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation== | ==Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation== | ||
<StructureSection load='4j2q' size='340' side='right' caption='[[4j2q]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='4j2q' size='340' side='right'caption='[[4j2q]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4j2q]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4j2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2Q FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2q OCA], [https://pdbe.org/4j2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2q RCSB], [https://www.ebi.ac.uk/pdbsum/4j2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Arrestin|Arrestin]] | *[[Arrestin 3D structures|Arrestin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bos taurus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Choe H-W]] | ||
[[Category: Kim YJ]] | |||
[[Category: Scheerer P]] | |||
[[Category: | |||
[[Category: | |||