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==GCN4 LEUCINE ZIPPER MUTANT WITH TWO VXXNXXX MOTIFS COORDINATING CHLORIDE==
==GCN4 leucine zipper mutant with two VxxNxxx motifs coordinating chloride==
<StructureSection load='2wpz' size='340' side='right' caption='[[2wpz]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='2wpz' size='340' side='right'caption='[[2wpz]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wpz]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wpz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rb5|1rb5]], [[1gcm|1gcm]], [[1unt|1unt]], [[1llm|1llm]], [[2zta|2zta]], [[1uo2|1uo2]], [[1unw|1unw]], [[2ccf|2ccf]], [[1ce9|1ce9]], [[2wg6|2wg6]], [[1tmz|1tmz]], [[1zil|1zil]], [[2ccn|2ccn]], [[1w5l|1w5l]], [[1rb6|1rb6]], [[1zij|1zij]], [[1unz|1unz]], [[1w5k|1w5k]], [[1piq|1piq]], [[1unx|1unx]], [[1uny|1uny]], [[1zik|1zik]], [[1ysa|1ysa]], [[1w5h|1w5h]], [[1ij2|1ij2]], [[1unv|1unv]], [[1uo3|1uo3]], [[2cce|2cce]], [[1ij0|1ij0]], [[1w5g|1w5g]], [[1unu|1unu]], [[2b22|2b22]], [[1ld4|1ld4]], [[2b1f|2b1f]], [[2wg5|2wg5]], [[1uo0|1uo0]], [[1uo1|1uo1]], [[1swi|1swi]], [[1w5i|1w5i]], [[2dgc|2dgc]], [[2d3e|2d3e]], [[1nkn|1nkn]], [[1gcl|1gcl]], [[1zii|1zii]], [[1kql|1kql]], [[1uo5|1uo5]], [[1rb4|1rb4]], [[1ihq|1ihq]], [[1uo4|1uo4]], [[1ij3|1ij3]], [[1zta|1zta]], [[1w5j|1w5j]], [[1ij1|1ij1]], [[1dgc|1dgc]], [[1rb1|1rb1]], [[1zim|1zim]], [[1gzl|1gzl]], [[2bni|2bni]], [[2wps|2wps]], [[2wpy|2wpy]], [[2wq0|2wq0]], [[2wq3|2wq3]], [[2wpq|2wpq]], [[2wq1|2wq1]], [[2wq2|2wq2]], [[2wpr|2wpr]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpz OCA], [https://pdbe.org/2wpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpz RCSB], [https://www.ebi.ac.uk/pdbsum/2wpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpz OCA], [http://pdbe.org/2wpz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpz RCSB], [http://www.ebi.ac.uk/pdbsum/2wpz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Gcn4|Gcn4]]
*[[Gcn4 3D Structures|Gcn4 3D Structures]]
*[[Gnc4 3D Structures|Gnc4 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Albrecht, R]]
[[Category: Large Structures]]
[[Category: Alvarez, B Hernandez]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Hartmann, M D]]
[[Category: Albrecht R]]
[[Category: Lupas, A N]]
[[Category: Hartmann MD]]
[[Category: Zeth, K]]
[[Category: Hernandez Alvarez B]]
[[Category: Activator]]
[[Category: Lupas AN]]
[[Category: Amino-acid biosynthesis]]
[[Category: Zeth K]]
[[Category: Dna-binding]]
[[Category: Ion coordination]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Polar core residue]]
[[Category: Protein export]]
[[Category: Taa]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Trimeric autotransporter adhesin]]

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