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==Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation==
==Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation==
<StructureSection load='3zju' size='340' side='right' caption='[[3zju]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3zju' size='340' side='right'caption='[[3zju]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zju]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZJU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zju]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZJU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DJF:[(1S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-2-(3-OXIDANYLPROPOXY)SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,9-8-OXA-9-BORANUIDABICYCLO[4.3.0]NONA-1(6),2,4-TRIENE]-8-YL]METHYL+DIHYDROGEN+PHOSPHATE'>DJF</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DJF:[(1S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-2-(3-OXIDANYLPROPOXY)SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,9-8-OXA-9-BORANUIDABICYCLO[4.3.0]NONA-1(6),2,4-TRIENE]-8-YL]METHYL+DIHYDROGEN+PHOSPHATE'>DJF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zjt|3zjt]], [[3zjv|3zjv]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zju OCA], [https://pdbe.org/3zju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zju RCSB], [https://www.ebi.ac.uk/pdbsum/3zju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zju ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucine--tRNA_ligase Leucine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.4 6.1.1.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zju OCA], [http://pdbe.org/3zju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zju RCSB], [http://www.ebi.ac.uk/pdbsum/3zju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zju ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYL_ECOLI SYL_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[TRNA|TRNA]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Leucine--tRNA ligase]]
[[Category: Escherichia coli K-12]]
[[Category: Akama, T]]
[[Category: Large Structures]]
[[Category: Alley, M R.K]]
[[Category: Akama T]]
[[Category: Anugula, M R]]
[[Category: Alley MRK]]
[[Category: Baker, S J]]
[[Category: Anugula MR]]
[[Category: Bu, W]]
[[Category: Baker SJ]]
[[Category: Crepin, T]]
[[Category: Bu W]]
[[Category: Cusack, S]]
[[Category: Crepin T]]
[[Category: DeMarsh, P L]]
[[Category: Cusack S]]
[[Category: Feng, L]]
[[Category: DeMarsh PL]]
[[Category: Freund, Y R]]
[[Category: Feng L]]
[[Category: Hernandez, V]]
[[Category: Freund YR]]
[[Category: Keramane, E M]]
[[Category: Hernandez V]]
[[Category: Liu, L]]
[[Category: Keramane EM]]
[[Category: Livermore, D M]]
[[Category: Liu L]]
[[Category: Mao, W]]
[[Category: Livermore DM]]
[[Category: Meewan, M]]
[[Category: Mao W]]
[[Category: Mohan, M]]
[[Category: Meewan M]]
[[Category: Mushtaq, S]]
[[Category: Mohan M]]
[[Category: Nieman, J A]]
[[Category: Mushtaq S]]
[[Category: OLeary, A]]
[[Category: Nieman JA]]
[[Category: Palencia, A]]
[[Category: OLeary A]]
[[Category: Plattner, J J]]
[[Category: Palencia A]]
[[Category: Reddy, D S]]
[[Category: Plattner JJ]]
[[Category: Rock, F L]]
[[Category: Reddy DS]]
[[Category: Savariraj, K]]
[[Category: Rock FL]]
[[Category: Sexton, H]]
[[Category: Savariraj K]]
[[Category: Sharma, R]]
[[Category: Sexton H]]
[[Category: Sheoran, A]]
[[Category: Sharma R]]
[[Category: Simon, N L]]
[[Category: Sheoran A]]
[[Category: Singh, R]]
[[Category: Simon NL]]
[[Category: Subedi, R]]
[[Category: Singh R]]
[[Category: Warner, M]]
[[Category: Subedi R]]
[[Category: Zhang, Y]]
[[Category: Warner M]]
[[Category: Zhou, Y]]
[[Category: Zhang Y]]
[[Category: Aminoacyl trna synthetase]]
[[Category: Zhou Y]]
[[Category: Atp binding]]
[[Category: Class i aminoacyl-trna synthetase]]
[[Category: Editing synthetase]]
[[Category: Ligase-rna complex]]
[[Category: Protein biosynthesis]]

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