4iy0: Difference between revisions
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==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | ==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | ||
<StructureSection load='4iy0' size='340' side='right' caption='[[4iy0]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4iy0' size='340' side='right'caption='[[4iy0]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IY0 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy0 OCA], [https://pdbe.org/4iy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iy0 RCSB], [https://www.ebi.ac.uk/pdbsum/4iy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iy0 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Accardi | [[Category: Large Structures]] | ||
[[Category: Corral-Rodriguez | [[Category: Accardi A]] | ||
[[Category: Diercks | [[Category: Corral-Rodriguez MA]] | ||
[[Category: Encinar | [[Category: Diercks T]] | ||
[[Category: Ereno-Orbea | [[Category: Encinar JA]] | ||
[[Category: Gomez-Garcia | [[Category: Ereno-Orbea J]] | ||
[[Category: Martinez-Cruz | [[Category: Gomez-Garcia I]] | ||
[[Category: Muller | [[Category: Martinez-Cruz LA]] | ||
[[Category: Oyenarte | [[Category: Muller D]] | ||
[[Category: Spiwok | [[Category: Oyenarte I]] | ||
[[Category: Stuiver | [[Category: Spiwok V]] | ||
[[Category: Terashima | [[Category: Stuiver M]] | ||
[[Category: Terashima H]] | |||