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==Crystal structure of ragweed allergen Amb a 8==
==Crystal structure of ragweed allergen Amb a 8==
<StructureSection load='5em1' size='340' side='right' caption='[[5em1]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5em1' size='340' side='right'caption='[[5em1]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5em1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EM1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EM1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5em1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ambrosia_artemisiifolia Ambrosia artemisiifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EM1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5em0|5em0]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5em1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5em1 OCA], [https://pdbe.org/5em1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5em1 RCSB], [https://www.ebi.ac.uk/pdbsum/5em1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5em1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5em1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5em1 OCA], [http://pdbe.org/5em1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5em1 RCSB], [http://www.ebi.ac.uk/pdbsum/5em1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5em1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q2KN24_AMBAR Q2KN24_AMBAR]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.[RuleBase:RU003908]  
[https://www.uniprot.org/uniprot/Q2KN24_AMBAR Q2KN24_AMBAR] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.[RuleBase:RU003908]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5em1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5em1" style="background-color:#fffaf0;"></div>
==See Also==
*[[Profilin 3D Structures|Profilin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chruszcz, M]]
[[Category: Ambrosia artemisiifolia]]
[[Category: He, J Z]]
[[Category: Large Structures]]
[[Category: Offermann, L R]]
[[Category: Chruszcz M]]
[[Category: Perdue, M L]]
[[Category: He JZ]]
[[Category: Allergen]]
[[Category: Offermann LR]]
[[Category: Perdue ML]]

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