4h5b: Difference between revisions

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 ==Crystal Structure of DR_1245 from Deinococcus radiodurans==
-<StructureSection load='4h5b' size='340' side='right' caption='[[4h5b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+<StructureSection load='4h5b' size='340' side='right'caption='[[4h5b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4h5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H5B FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4h5b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H5B FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DR_1245 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243230 DEIRA])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h5b OCA], [http://pdbe.org/4h5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4h5b RCSB], [http://www.ebi.ac.uk/pdbsum/4h5b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4h5b ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h5b OCA], [https://pdbe.org/4h5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h5b RCSB], [https://www.ebi.ac.uk/pdbsum/4h5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h5b ProSAT]</span></td></tr>
 </table>
-<div style="background-color:#fffaf0;">
+== Function ==
-== Publication Abstract from PubMed ==
+[https://www.uniprot.org/uniprot/Q9RUY5_DEIRA Q9RUY5_DEIRA]
-The bacterium Deinococcus radiodurans exhibits an extreme resistance to ionizing radiation. A small subset of Deinococcus genus-specific genes were shown to be up-regulated upon exposure to ionizing radiation and to play a role in genome reconstitution. These genes include an SSB-like protein called DdrB. Here, we identified a novel protein encoded by the dr1245 gene as an interacting partner of DdrB. A strain devoid of the DR1245 protein is impaired in growth, exhibiting a generation time approximately threefold that of the wild type strain while radioresistance is not affected. We determined the three-dimensional structure of DR1245, revealing a relationship with type III secretion system chaperones and YbjN family proteins. Thus, DR1245 may display some chaperone activity towards DdrB and possibly other substrates.
-The Deinococcus radiodurans DR1245 Protein, a DdrB Partner Homologous to YbjN Proteins and Reminiscent of Type III Secretion System Chaperones.,Norais C, Servant P, Bouthier-de-la-Tour C, Coureux PD, Ithurbide S, Vannier F, Guerin PP, Dulberger CL, Satyshur KA, Keck JL, Armengaud J, Cox MM, Sommer S PLoS One. 2013;8(2):e56558. doi: 10.1371/journal.pone.0056558. Epub 2013 Feb 18. PMID:23441204<ref>PMID:23441204</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 4h5b" style="background-color:#fffaf0;"></div>
-== References ==
-<references/>
 __TOC__
 </StructureSection>
-[[Category: Deira]]
+[[Category: Deinococcus radiodurans R1]]
-[[Category: Armengaud, J]]
+[[Category: Large Structures]]
-[[Category: Bouthier-de-la-Tour, C]]
+[[Category: Armengaud J]]
-[[Category: Coureux, P D]]
+[[Category: Bouthier-de-la-Tour C]]
-[[Category: Cox, M M]]
+[[Category: Coureux PD]]
-[[Category: Dulberger, C L]]
+[[Category: Cox MM]]
-[[Category: Guerin, P]]
+[[Category: Dulberger CL]]
-[[Category: Ithurbide, S]]
+[[Category: Guerin P]]
-[[Category: Keck, J L]]
+[[Category: Ithurbide S]]
-[[Category: Norais, C]]
+[[Category: Keck JL]]
-[[Category: Satyshur, K A]]
+[[Category: Norais C]]
-[[Category: Servant, P]]
+[[Category: Satyshur KA]]
-[[Category: Sommer, S]]
+[[Category: Servant P]]
-[[Category: Vannier, F]]
+[[Category: Sommer S]]
-[[Category: Secretion chaperone-like fold]]
+[[Category: Vannier F]]
-[[Category: Unknown function]]