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==Crystal Structure of Rat Galectin-1 in Complex with Lactose==
==Crystal Structure of Rat Galectin-1 in Complex with Lactose==
<StructureSection load='4ga9' size='340' side='right' caption='[[4ga9]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='4ga9' size='340' side='right'caption='[[4ga9]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ga9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GA9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ga9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GA9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBT:ALPHA-LACTOSE'>LBT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m2m|3m2m]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Lgals1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ga9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ga9 OCA], [https://pdbe.org/4ga9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ga9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ga9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ga9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ga9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ga9 OCA], [http://pdbe.org/4ga9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ga9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ga9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ga9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LEG1_RAT LEG1_RAT]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).  
[https://www.uniprot.org/uniprot/LEG1_RAT LEG1_RAT] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).


==See Also==
==See Also==
*[[Galectin|Galectin]]
*[[Galectin 3D structures|Galectin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Hirsch, J A]]
[[Category: Rattus norvegicus]]
[[Category: Segev, O]]
[[Category: Hirsch JA]]
[[Category: Carbohydrate-binding protein]]
[[Category: Segev O]]
[[Category: Jellyroll like/beta barrel]]

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