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==Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75==
==Crystal structure of a blue-light absorbing proteorhodopsin double-mutant D97N/Q105L from HOT75==
<StructureSection load='4knf' size='340' side='right' caption='[[4knf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='4knf' size='340' side='right'caption='[[4knf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4knf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gamma_proteobacterium_'hot_75m4' Gamma proteobacterium 'hot 75m4']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KNF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4knf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gamma_proteobacterium_'Hot_75m4' Gamma proteobacterium 'Hot 75m4']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KNF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kly|4kly]], [[4jq6|4jq6]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4knf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4knf OCA], [http://pdbe.org/4knf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4knf RCSB], [http://www.ebi.ac.uk/pdbsum/4knf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4knf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4knf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4knf OCA], [https://pdbe.org/4knf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4knf RCSB], [https://www.ebi.ac.uk/pdbsum/4knf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4knf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRRB_PRB02 PRRB_PRB02]] Light-driven proton pump. May have a regulatory rather than energy harvesting function, based on light-induced opening of proton channels, to modulate cell physiology depending on light intensity variations. Could be, therefore, a sensory rhodopsin, potentially associated with a transducer component.  
[https://www.uniprot.org/uniprot/PRRB_PRB02 PRRB_PRB02] Light-driven proton pump. May have a regulatory rather than energy harvesting function, based on light-induced opening of proton channels, to modulate cell physiology depending on light intensity variations. Could be, therefore, a sensory rhodopsin, potentially associated with a transducer component.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Rhodopsin|Rhodopsin]]
*[[Bacteriorhodopsin 3D structures|Bacteriorhodopsin 3D structures]]
*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gamma proteobacterium 'hot 75m4']]
[[Category: Gamma proteobacterium 'Hot 75m4']]
[[Category: Gao, Y]]
[[Category: Large Structures]]
[[Category: Luecke, H]]
[[Category: Gao Y]]
[[Category: Ozorowski, G]]
[[Category: Luecke H]]
[[Category: Ran, T]]
[[Category: Ozorowski G]]
[[Category: Wang, W]]
[[Category: Ran T]]
[[Category: Ion transport]]
[[Category: Wang W]]
[[Category: Membrane]]
[[Category: Proton pump]]
[[Category: Proton transport]]
[[Category: Retinylidene schiff base]]

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