1mh2: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1mh2.jpg|left|200px]]


{{Structure
==Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)==
|PDB= 1mh2 |SIZE=350|CAPTION= <scene name='initialview01'>1mh2</scene>, resolution 2.70&Aring;
<StructureSection load='1mh2' size='340' side='right'caption='[[1mh2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1mh2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MH2 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mh2 OCA], [https://pdbe.org/1mh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mh2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mh2 ProSAT]</span></td></tr>
|RELATEDENTRY=[[1lfj|1LFJ]], [[1lff|1LFF]], [[1ln8|1LN8]], [[1mf4|1MF4]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mh2 OCA], [http://www.ebi.ac.uk/pdbsum/1mh2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mh2 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PA2B1_NAJSG PA2B1_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/1mh2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mh2 ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)'''
==See Also==
 
*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1MH2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH2 OCA].
[[Category: Large Structures]]
[[Category: Naja sagittifera]]
[[Category: Naja sagittifera]]
[[Category: Phospholipase A(2)]]
[[Category: Jabeen T]]
[[Category: Protein complex]]
[[Category: Paramasivam M]]
[[Category: Jabeen, T.]]
[[Category: Sharma S]]
[[Category: Paramasivam, M.]]
[[Category: Singh N]]
[[Category: Sharma, S.]]
[[Category: Singh RK]]
[[Category: Singh, N.]]
[[Category: Singh TP]]
[[Category: Singh, R K.]]
[[Category: Srinivasan A]]
[[Category: Singh, T P.]]
[[Category: Varma AK]]
[[Category: Srinivasan, A.]]
[[Category: Varma, A K.]]
[[Category: complex]]
[[Category: enzyme]]
[[Category: phospholipase a2]]
[[Category: phospholipid]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:16:01 2008''

Latest revision as of 10:01, 30 October 2024

Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera)

Structural highlights

1mh2 is a 2 chain structure with sequence from Naja sagittifera. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PA2B1_NAJSG PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mh2, resolution 2.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1mh2&oldid=4199685"