2v8z: Difference between revisions
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== | ==Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12== | ||
<StructureSection load='2v8z' size='340' side='right' caption='[[2v8z]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2v8z' size='340' side='right'caption='[[2v8z]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2v8z]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2v8z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8Z FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8z OCA], [https://pdbe.org/2v8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8z RCSB], [https://www.ebi.ac.uk/pdbsum/2v8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8z_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8z_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 24: | Line 24: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: Albeck | [[Category: Large Structures]] | ||
[[Category: Bourenkov | [[Category: Albeck S]] | ||
[[Category: Dym | [[Category: Bourenkov G]] | ||
[[Category: Greenblatt | [[Category: Dym O]] | ||
[[Category: Krishnaswamy | [[Category: Greenblatt HM]] | ||
[[Category: Lamzin | [[Category: Krishnaswamy S]] | ||
[[Category: Manicka | [[Category: Lamzin V]] | ||
[[Category: Peleg | [[Category: Manicka S]] | ||
[[Category: Sussman | [[Category: Peleg Y]] | ||
[[Category: Unger | [[Category: Sussman JL]] | ||
[[Category: Unger T]] | |||
Latest revision as of 18:10, 13 December 2023
Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12
Structural highlights
FunctionYAGE_ECOLI Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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