4nqn: Difference between revisions
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==Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand== | ==Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand== | ||
<StructureSection load='4nqn' size='340' side='right' caption='[[4nqn]], [[Resolution|resolution]] 1.73Å' scene=''> | <StructureSection load='4nqn' size='340' side='right'caption='[[4nqn]], [[Resolution|resolution]] 1.73Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4nqn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4nqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NQN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y1Z:2-CHLORO-N-[5-(3-METHYL[1,2,4]TRIAZOLO[3,4-A]PHTHALAZIN-6-YL)-2-(MORPHOLIN-4-YL)PHENYL]BENZENESULFONAMIDE'>Y1Z</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nqn OCA], [https://pdbe.org/4nqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nqn RCSB], [https://www.ebi.ac.uk/pdbsum/4nqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nqn ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription. | |||
==See Also== | ==See Also== | ||
*[[Bromodomain-containing protein|Bromodomain-containing protein]] | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Fedorov | [[Category: Fedorov O]] | ||
[[Category: Felletar | [[Category: Felletar I]] | ||
[[Category: Filippakopoulos | [[Category: Filippakopoulos P]] | ||
[[Category: Knapp | [[Category: Knapp S]] | ||
[[Category: Martin | [[Category: Martin S]] | ||
[[Category: Picaud | [[Category: Picaud S]] | ||
[[Category: | [[Category: Von Delft F]] | ||