2v37: Difference between revisions
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== | ==Solution structure of the N-terminal extracellular domain of human T- cadherin== | ||
<StructureSection load='2v37' size='340' side='right' caption='[[2v37]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2v37' size='340' side='right'caption='[[2v37]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2v37]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2v37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V37 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v37 OCA], [https://pdbe.org/2v37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v37 RCSB], [https://www.ebi.ac.uk/pdbsum/2v37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v37 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CAD13_HUMAN CAD13_HUMAN]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.<ref>PMID:10737605</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v37_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v37_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
*[[Cadherin|Cadherin]] | *[[Cadherin 3D structures|Cadherin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Ahrens, T]] | [[Category: Ahrens, T]] | ||
[[Category: Bang, E J]] | [[Category: Bang, E J]] | ||
| Line 41: | Line 42: | ||
[[Category: Haeussinger, D]] | [[Category: Haeussinger, D]] | ||
[[Category: Adiponectin receptor]] | [[Category: Adiponectin receptor]] | ||
[[Category: Calcium]] | |||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Cell-cell adhesion]] | [[Category: Cell-cell adhesion]] | ||
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[[Category: Lipoprotein]] | [[Category: Lipoprotein]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Polymorphism]] | |||
[[Category: T-cadherin]] | [[Category: T-cadherin]] | ||