3q3y: Difference between revisions

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 ==Complex structure of HEVB EV93 main protease 3C with Compound 1 (AG7404)==
-<StructureSection load='3q3y' size='340' side='right' caption='[[3q3y]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
+<StructureSection load='3q3y' size='340' side='right'caption='[[3q3y]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3q3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterovirus_b Enterovirus b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q3Y FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3q3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterovirus_B Enterovirus B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q3Y FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene>, <scene name='pdbligand=XNV:ETHYL+(4R)-4-({(2S)-2-[3-{[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYL]AMINO}-2-OXOPYRIDIN-1(2H)-YL]PENT-4-YNOYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>XNV</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q3x|3q3x]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene>, <scene name='pdbligand=XNV:ETHYL+(4R)-4-({(2S)-2-[3-{[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYL]AMINO}-2-OXOPYRIDIN-1(2H)-YL]PENT-4-YNOYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE'>XNV</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=138949 Enterovirus B])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3y OCA], [https://pdbe.org/3q3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q3y RCSB], [https://www.ebi.ac.uk/pdbsum/3q3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q3y ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3y OCA], [http://pdbe.org/3q3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q3y RCSB], [http://www.ebi.ac.uk/pdbsum/3q3y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q3y ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q5DSM6_9ENTO Q5DSM6_9ENTO]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 21: @@
 ==See Also==
-*[[3C protease|3C protease]]
+*[[Virus protease 3D structures|Virus protease 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Enterovirus b]]
+[[Category: Enterovirus B]]
-[[Category: Picornain 3C]]
+[[Category: Large Structures]]
-[[Category: Arnan, C]]
+[[Category: Arnan C]]
-[[Category: Canard, B]]
+[[Category: Canard B]]
-[[Category: Coll, M]]
+[[Category: Coll M]]
-[[Category: Costenaro, L]]
+[[Category: Costenaro L]]
-[[Category: Coutard, B]]
+[[Category: Coutard B]]
-[[Category: Kaczmarska, Z]]
+[[Category: Kaczmarska Z]]
-[[Category: Norder, H]]
+[[Category: Norder H]]
-[[Category: Sola, M]]
+[[Category: Sola M]]
-[[Category: Cysteine trypsin-like protease]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]