Sandbox 122: Difference between revisions
No edit summary |
No edit summary |
||
| Line 12: | Line 12: | ||
Recognition the PY-NLS by Kapβ2 follows a certain guidelines: | Recognition the PY-NLS by Kapβ2 follows a certain guidelines: | ||
#PY-NLS, when not bound to Kapβ2, lacks a secondary structure. | #PY-NLS, when not bound to Kapβ2, lacks a secondary structure. | ||
#PY-NLS hass an overall <scene name='37/372723/Positive_interaction_nls_only/ | #PY-NLS hass an overall <scene name='37/372723/Positive_interaction_nls_only/3'>positive charge</scene> allowing for electrostatic compatibility with Kapβ2. | ||
#General sequence for the PY-NLS is either a hydrophobic or base at the motif at N-terminus and R-X2-5- P-Y motif at the C-terminus | #General sequence for the PY-NLS is either a hydrophobic or base at the motif at N-terminus and R-X2-5- P-Y motif at the C-terminus | ||