4np9: Difference between revisions

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==Structure of Rabphilin C2A domain bound to IP3==
==Structure of Rabphilin C2A domain bound to IP3==
<StructureSection load='4np9' size='340' side='right' caption='[[4np9]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='4np9' size='340' side='right'caption='[[4np9]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4np9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NP9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4np9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NP9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ns0|4ns0]], [[2chd|2chd]], [[2k3h|2k3h]], [[2cm5|2cm5]], [[2cm6|2cm6]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rph3a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4np9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4np9 OCA], [https://pdbe.org/4np9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4np9 RCSB], [https://www.ebi.ac.uk/pdbsum/4np9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4np9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4np9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4np9 OCA], [http://pdbe.org/4np9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4np9 RCSB], [http://www.ebi.ac.uk/pdbsum/4np9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4np9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.  
[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4np9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4np9" style="background-color:#fffaf0;"></div>
==See Also==
*[[Exophilin|Exophilin]]
*[[Exophilin 3D structures|Exophilin 3D structures]]
*[[Rabphilin|Rabphilin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Buxaderas, M]]
[[Category: Rattus norvegicus]]
[[Category: Corbalan-Garcia, S]]
[[Category: Buxaderas M]]
[[Category: Ferrer-Orta, C]]
[[Category: Corbalan-Garcia S]]
[[Category: Gomez-Fernandez, J C]]
[[Category: Ferrer-Orta C]]
[[Category: Guerra, P]]
[[Category: Gomez-Fernandez JC]]
[[Category: Guerrero-Valero, M]]
[[Category: Guerra P]]
[[Category: Guillen, J]]
[[Category: Guerrero-Valero M]]
[[Category: Luengo-Gil, G]]
[[Category: Guillen J]]
[[Category: Perez-Sanchez, D]]
[[Category: Luengo-Gil G]]
[[Category: Pous, J]]
[[Category: Perez-Sanchez D]]
[[Category: Verdaguer, N]]
[[Category: Pous J]]
[[Category: C-2 domain fold]]
[[Category: Verdaguer N]]
[[Category: C2 domain]]
[[Category: C2a]]
[[Category: Calcium binding]]
[[Category: Exophilin-1]]
[[Category: Protein transport]]
[[Category: Rabphilin-3a]]
[[Category: Synaptic exocytosis metal-binding]]

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