4a0q: Difference between revisions
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==Activated Conformation of Integrin alpha1 I-Domain mutant== | ==Activated Conformation of Integrin alpha1 I-Domain mutant== | ||
<StructureSection load='4a0q' size='340' side='right' caption='[[4a0q]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4a0q' size='340' side='right'caption='[[4a0q]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a0q]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4a0q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A0Q FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0q OCA], [https://pdbe.org/4a0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a0q RCSB], [https://www.ebi.ac.uk/pdbsum/4a0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ITA1_HUMAN ITA1_HUMAN] Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Integrin|Integrin]] | *[[Integrin 3D structures|Integrin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Bligt | [[Category: Large Structures]] | ||
[[Category: Brandt | [[Category: Bligt E]] | ||
[[Category: Heino | [[Category: Brandt A-M]] | ||
[[Category: Jokinen | [[Category: Heino J]] | ||
[[Category: Kapyla | [[Category: Jokinen J]] | ||
[[Category: Lahti | [[Category: Kapyla J]] | ||
[[Category: Niskanen | [[Category: Lahti M]] | ||
[[Category: Parkash | [[Category: Niskanen H]] | ||
[[Category: Patrikainen | [[Category: Parkash V]] | ||
[[Category: Salminen | [[Category: Patrikainen P]] | ||
[[Category: Salminen TA]] | |||