4c8g: Difference between revisions

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==IspF (Burkholderia cenocepacia) CMP complex==
==IspF (Burkholderia cenocepacia) CMP complex==
<StructureSection load='4c8g' size='340' side='right' caption='[[4c8g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4c8g' size='340' side='right'caption='[[4c8g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4c8g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Burcj Burcj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8G FirstGlance]. <br>
<table><tr><td colspan='2'>[[4c8g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c81|4c81]], [[4c82|4c82]], [[4c8e|4c8e]], [[4c8i|4c8i]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8g OCA], [https://pdbe.org/4c8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8g RCSB], [https://www.ebi.ac.uk/pdbsum/4c8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8g OCA], [http://pdbe.org/4c8g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c8g RCSB], [http://www.ebi.ac.uk/pdbsum/4c8g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ISPF_BURCJ ISPF_BURCJ]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).  
[https://www.uniprot.org/uniprot/ISPF_BURCJ ISPF_BURCJ] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[MECDP synthase|MECDP synthase]]
*[[MECDP synthase 3D structures|MECDP synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: Burkholderia cenocepacia J2315]]
[[Category: Burcj]]
[[Category: Large Structures]]
[[Category: Dawson, A]]
[[Category: Dawson A]]
[[Category: Fyfe, P K]]
[[Category: Fyfe PK]]
[[Category: Hunter, W N]]
[[Category: Hunter WN]]
[[Category: Kalinowska-Tluscik, J]]
[[Category: Kalinowska-Tluscik J]]
[[Category: Rourke, P E.F O]]
[[Category: O'Rourke PEF]]
[[Category: Lyase]]

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