5co5: Difference between revisions

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==Crystal structure of Ac-AChBP in complex with conotoxin GIC==
==Crystal structure of Ac-AChBP in complex with conotoxin GIC==
<StructureSection load='5co5' size='340' side='right' caption='[[5co5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5co5' size='340' side='right'caption='[[5co5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5co5]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CO5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5co5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica] and [https://en.wikipedia.org/wiki/Conus_geographus Conus geographus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CO5 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5co5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5co5 OCA], [http://pdbe.org/5co5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5co5 RCSB], [http://www.ebi.ac.uk/pdbsum/5co5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5co5 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5co5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5co5 OCA], [https://pdbe.org/5co5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5co5 RCSB], [https://www.ebi.ac.uk/pdbsum/5co5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5co5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CA1C_CONGE CA1C_CONGE]] Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them. This toxin reversibly blocks neuronal nAChRs (alpha-3/beta-2 = alpha-6 or -3/beta-2 or -3 > alpha-3/beta-4 = alpha-4/beta-2).
[https://www.uniprot.org/uniprot/Q8WSF8_APLCA Q8WSF8_APLCA]  
 
==See Also==
*[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lin, B]]
[[Category: Aplysia californica]]
[[Category: Luo, S L]]
[[Category: Conus geographus]]
[[Category: Wang, X Q]]
[[Category: Large Structures]]
[[Category: Xu, M Y]]
[[Category: Lin B]]
[[Category: Achbp]]
[[Category: Luo SL]]
[[Category: Gic]]
[[Category: Wang XQ]]
[[Category: Metal binding protein-toxin complex]]
[[Category: Xu MY]]

Latest revision as of 10:02, 17 October 2024

Crystal structure of Ac-AChBP in complex with conotoxin GICCrystal structure of Ac-AChBP in complex with conotoxin GIC

Structural highlights

5co5 is a 10 chain structure with sequence from Aplysia californica and Conus geographus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q8WSF8_APLCA

See Also

5co5, resolution 2.10Å

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