1ih1: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1ih1.gif|left|200px]]
- {{Structure
+==Crystal Structure of the B-DNA Hexamer GGCGCC with Cobalt Hexamine Resolved to 2.0 Angstroms==
-|PDB= 1ih1 |SIZE=350|CAPTION= <scene name='initialview01'>1ih1</scene>, resolution 2.0&Aring;
+<StructureSection load='1ih1' size='340' side='right'caption='[[1ih1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE+ION'>NCO</scene>
+<table><tr><td colspan='2'>[[1ih1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IH1 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ih1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih1 OCA], [https://pdbe.org/1ih1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ih1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ih1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih1 ProSAT]</span></td></tr>
-|RELATEDENTRY=[[1f69|1F69]], [[1ih2|1IH2]], [[1ih3|1IH3]], [[1ih4|1IH4]], [[1ih6|1IH6]]
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ih1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih1 OCA], [http://www.ebi.ac.uk/pdbsum/1ih1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ih1 RCSB]</span>
+__TOC__
-}}
+</StructureSection>
+[[Category: Large Structures]]
-'''Crystal Structure of the B-DNA Hexamer GGCGCC with Cobalt Hexamine Resolved to 2.0 Angstroms'''
+[[Category: Henderson K]]
+[[Category: Ho PS]]
+[[Category: Vargason JM]]
-==Overview==
-The transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway.
-==About this Structure==
-IH1 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH1 OCA].
-==Reference==
-A crystallographic map of the transition from B-DNA to A-DNA., Vargason JM, Henderson K, Ho PS, Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11390969 11390969]
-[[Category: Protein complex]]
-[[Category: Henderson, K.]]
-[[Category: Ho, P S.]]
-[[Category: Vargason, J M.]]
-[[Category: b to a dna transition]]
-[[Category: dna transition]]
-[[Category: structural transition]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:19:40 2008''