5aoy: Difference between revisions
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==Structure of mouse Endonuclease V== | ==Structure of mouse Endonuclease V== | ||
<StructureSection load='5aoy' size='340' side='right' caption='[[5aoy]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='5aoy' size='340' side='right'caption='[[5aoy]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5aoy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOY OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5aoy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AOY FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aoy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aoy OCA], [https://pdbe.org/5aoy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aoy RCSB], [https://www.ebi.ac.uk/pdbsum/5aoy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aoy ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ENDOV_MOUSE ENDOV_MOUSE] Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5aoy" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5aoy" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Endonuclease 3D structures|Endonuclease 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: | [[Category: Alseth I]] | ||
[[Category: | [[Category: Bjoras M]] | ||
[[Category: | [[Category: Dalhus B]] | ||
[[Category: | [[Category: Nawaz MS]] | ||
[[Category: | [[Category: Ronander ME]] | ||
[[Category: | [[Category: Solvoll AM]] | ||
[[Category: | [[Category: Strom-Andersen P]] | ||
[[Category: | [[Category: Vik ES]] | ||