5j4h: Difference between revisions
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New page: '''Unreleased structure''' The entry 5j4h is ON HOLD until Paper Publication Authors: Fischer, G., Marsh, M., Moschetti, T., Sharpe, T., Scott, D., Morgan, M., Ng, H., Skidmore, J., Ven... |
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==Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid== | |||
<StructureSection load='5j4h' size='340' side='right'caption='[[5j4h]], [[Resolution|resolution]] 1.37Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5j4h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J4H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.374Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1F1:1H-INDOLE-6-CARBOXYLIC+ACID'>1F1</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4h OCA], [https://pdbe.org/5j4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j4h RCSB], [https://www.ebi.ac.uk/pdbsum/5j4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4h ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | |||
==See Also== | |||
*[[Resolvase 3D structures|Resolvase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pyrococcus furiosus DSM 3638]] | ||
[[Category: | [[Category: Abell C]] | ||
[[Category: | [[Category: Blundell TL]] | ||
[[Category: | [[Category: Fischer G]] | ||
[[Category: | [[Category: Hyvonen M]] | ||
[[Category: | [[Category: Marsh M]] | ||
[[Category: | [[Category: Morgan M]] | ||
[[Category: Scott | [[Category: Moschetti T]] | ||
[[Category: | [[Category: Ng H]] | ||
[[Category: | [[Category: Scott D]] | ||
[[Category: | [[Category: Sharpe T]] | ||
[[Category: Skidmore J]] | |||
[[Category: Venkitaraman A]] | |||
Latest revision as of 10:24, 1 May 2024
Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acidStructure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid
Structural highlights
FunctionRADA_PYRFU Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. See Also |
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