4txj: Difference between revisions
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==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine== | ==Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine== | ||
<StructureSection load='4txj' size='340' side='right' caption='[[4txj]], [[Resolution|resolution]] 1.66Å' scene=''> | <StructureSection load='4txj' size='340' side='right'caption='[[4txj]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4txj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXJ OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4txj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TXJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.662Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4txj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txj OCA], [https://pdbe.org/4txj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4txj RCSB], [https://www.ebi.ac.uk/pdbsum/4txj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4txj ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/UPPA_SCHMA UPPA_SCHMA] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:26898674). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).<ref>PMID:26898674</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4txj" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4txj" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Brandao-Neto | [[Category: Schistosoma mansoni]] | ||
[[Category: Cassago | [[Category: Brandao-Neto J]] | ||
[[Category: DeMarco | [[Category: Cassago A]] | ||
[[Category: Marinho | [[Category: DeMarco R]] | ||
[[Category: Pereira | [[Category: Marinho A]] | ||
[[Category: Romanello | [[Category: Pereira HM]] | ||
[[Category: Torini | [[Category: Romanello L]] | ||
[[Category: Torini J]] | |||