5eqg: Difference between revisions

==MFS transporter in complex with inhibitor (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide==

<StructureSection load='5eqg' size='340' side='right' caption='[[5eqg]], [[Resolution|resolution]] 2.90&Aring;' scene=''>

<table><tr><td colspan='2'>[[5eqg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EQG FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5RE:(2~{S})-3-(4-FLUOROPHENYL)-2-[2-(3-HYDROXYPHENYL)ETHANOYLAMINO]-~{N}-[(1~{S})-1-PHENYLETHYL]PROPANAMIDE'>5RE</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pyp|4pyp]], [[5eqh|5eqh]], [[5eqi|5eqi]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqg OCA], [http://pdbe.org/5eqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eqg RCSB], [http://www.ebi.ac.uk/pdbsum/5eqg PDBsum]</span></td></tr>

[[http://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN]] Hereditary cryohydrocytosis with reduced stomatin;Paroxysmal exertion-induced dyskinesia;Encephalopathy due to GLUT1 deficiency;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Childhood absence epilepsy;Epilepsy with myoclonic-astatic seizures. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN]] Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.  

[[Category: Bringmann, P]]

[[Category: Caboni, L]]

[[Category: Finer-Moore, J]]

[[Category: Heisler, I]]

[[Category: Hillig, R]]

[[Category: Kapoor, K]]

[[Category: Muller, T]]

[[Category: Pedersen, B P]]

[[Category: Siebeneicher, H]]

[[Category: Stroud, R M]]

[[Category: Waight, A B]]

[[Category: Transport protein-inhibitor complex]]