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| {{STRUCTURE_1n3w| PDB=1n3w | SIZE=400| SCENE= |right|CAPTION=Maltose-binding protein complex with maltose, [[1n3w]] }}
| | <StructureSection load='1anf' size='350' side='right' caption='E. coli maltose-binding protein complex with maltose (PDB entry [[1anf]])' scene='47/471830/Cv/1'> |
| == Function == | | == Function == |
| '''Maltose-binding protein''' (MBP) or '''ABC maltose transporter''' is part of the maltose/maltodextrin system in ''E. coli'' which is responsible of the catabolism of maltodextrin. MBP binds maltodextrin when the latter diffuses into the periplasm and passes it to proteins involved in active transport<ref>PMID:10452611</ref>. | | '''Maltose-binding protein''' (MBP) or '''ABC maltose transporter''' is part of the maltose/maltodextrin system in ''E. coli'' which is responsible of the catabolism of maltodextrin. MBP binds maltodextrin when the latter diffuses into the periplasm and passes it to proteins involved in active transport<ref>PMID:10452611</ref>. |
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| == Structural highlights == | | == Structural highlights == |
| | The <scene name='47/471830/Cv/5'>MBP sugar binding cleft is rich with protein-ligand hydrogen bonds</scene><ref>PMID:9309217</ref>. Water molecules are shown as red spheres. |
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| ==3D structures of maltose-binding protein== | | ==3D structures of maltose-binding protein== |
| | [[Maltose-binding protein 3D structures]] |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | </StructureSection> |
| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *'''MBP'''
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| **[[1llx]], [[1jw4]], [[1lls]], [[1omp]] - MBP<br />
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| **[[3sey]], [[3sex]], [[3sew]], [[3sev]], [[3seu]], [[3set]], [[3ses]], [[3ser]], [[2v93]], [[1zkb]], [[1n3x]], [[1peb ]], [[1mbp]], [[1mpc]], [[3kjt]], [[1mdp]], [[1mdq]], [[1mbp]] - MBP (mutant)<br />
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| **[[2klf]], [[2d21]] – MBP – NMR<br />
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| **[[1ziu]] – MBP (mutant) + Ni<br />
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| **[[1zjl]] – MBP (mutant) + Zn<br />
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| **[[1zmg]] - MBP (mutant) + Cu<br />
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| **[[4log]] - MBP /nuclear receptor<br />
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| **[[4ogm]] - MBP /pilin<br />
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| **[[4pe2]] - MBP /pilA1<br />
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| **[[4khz]] - MBP MalK, MalF, MalG, MBP <br />
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| **[[3fh6]] - MBP MalK, MalF, MalG <br />
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| **[[2xd2]] – SpMBP – ''Streptococcus pneumoniae''
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| *MBP complex with saccharide
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| **[[1n3w]], [[1nl5]], [[1mpd]], [[1iud]], [[1jvx]], [[1jvy]] - MBP (mutant) + maltose<br />
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| **[[1anf]], [[1jw5]], [[2xz3]] - MBP + maltose<br />
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| **[[3mbp]] - MBP + maltotriose<br />
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| **[[4mbp]] - MBP + maltotetrose<br />
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| **[[1ez9]] - MBP + maltodextrin<br />
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| **[[3hpi]] – MBP (mutant) + sucrose<br />
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| **[[1lax]] - MBP (mutant) + glucose<br />
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| **[[2h25]], [[1ezo]], [[1dmb]] - MBP + β-cyclodextrin<br />
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| **[[1ezp]] - MBP (mutant) + β-cyclodextrin<br />
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| **[[1fqa]], [[1fqb]], [[1fqc]], [[1fqd]] - MBP + maltotetraitol<br />
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| **[[3puy]], [[3puz]] - MBP MalK, MalF, MalG, MBP + maltose + AMPPNP<br />
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| **[[3rlf]] - MBP MalK, MalF, MalG, MBP + maltose + AMPPNP<br />
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| **[[4jbw]] - MBP MalK, MalF, MalG + EIIAGLC<br />
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| **[[3pv0]] - MBP MalK, MalF, MalG, MBP + maltose <br />
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| **[[2r6g]], [[3puv]], [[3puw]], [[3pux]], [[4ki0]] - MBP MalK, MalF, MalG, MBP + maltose + nucleotide<br />
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| **[[3ob4]] - MBP AraH2 (mutant) + maltotriose<br />
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| **[[1elj]] – MBP + glucose – ''Pyrococcus furiosus''<br />
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| **[[3jyr]] – MBP + α-acarbose – ''Salmonella enterica''<br />
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| **[[2xd3]] – SpMBP + maltopentaose
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| *MBP complex with protein
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| **[[3pgf]] – MBP (mutant) + synthetic antigen binder<br />
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| **[[2r6g]], [[4khz]], [[4ki0]] - MBP + maltose transporter complex<br />
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| **[[3puv]], [[3puw]], [[3pux]] – MBP + maltose transporter complex + ADP <br />
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| **[[3rlf]] - MBP + maltose transporter complex + Mg-AMPPNP<br />
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| **[[1svx]] – MBP + ankyrin repeat protein OFF7<br />
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| **[[1nmu]] - MBP + ribosomal protein L30<br />
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| **[[1t0k]] - MBP + ribosomal protein L30 + RNA<br />
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| **[[3rum]] – MBP + ristocetin<br />
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| **[[4nuf]] - MBP /nuclear receptor + orphan nuclear receptor peptide<br />
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |