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New page: '''Unreleased structure''' The entry 5ign is ON HOLD Authors: Tallant, C., Clark, P.G.K., Vieira, L.C.C., Newman, J.A., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Dixon, D.J... |
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==Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe== | |||
<StructureSection load='5ign' size='340' side='right'caption='[[5ign]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ign]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IGN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [https://pdbe.org/5ign PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [https://www.ebi.ac.uk/pdbsum/5ign PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ign ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription. | |||
==See Also== | |||
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Brennan PE]] | ||
[[Category: | [[Category: Clark PGK]] | ||
[[Category: | [[Category: Dixon DJ]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: Fedorov O]] | ||
[[Category: | [[Category: Knapp S]] | ||
[[Category: | [[Category: Krojer T]] | ||
[[Category: | [[Category: Newman JA]] | ||
[[Category: | [[Category: Nunez-Alonso G]] | ||
[[Category: | [[Category: Picaud S]] | ||
[[Category: | [[Category: Tallant C]] | ||
[[Category: | [[Category: Vieira LCC]] | ||
[[Category: Von Delft F]] | |||
Latest revision as of 16:51, 30 August 2023
Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probeCrystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
Structural highlights
FunctionBRD9_HUMAN May play a role in chromatin remodeling and regulation of transcription. See Also |
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