Transfer RNA tour: Difference between revisions
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==tRNA== | ==tRNA== | ||
<StructureSection load='1tra' size=' | <StructureSection load='1tra' size='350' side='right' caption='phe-tRNA [[1tra]]' scene='72/725890/Trna_overview/1'> | ||
Source <ref>PMID:790568</ref> | Source <ref>PMID:790568</ref> | ||
== Structural highlights == | == Structural highlights == | ||
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The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>. | The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>. | ||
<B><FONT COLOR="#008aff">A9</FONT></B> is also involved in another type of tertiary interaction: it is <scene name='72/725890/Trna_tertwire/ | <B><FONT COLOR="#008aff">A9</FONT></B> is also involved in another type of tertiary interaction: it is <scene name='72/725890/Trna_tertwire/3'>intercalated between bases</scene> <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> and <B>G45</B>. In order to make room between these bases for <B><FONT COLOR="#008aff">A9</FONT></B> the backbone is extended by a C2' endo sugar pucker at <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B>. | ||