4tmw: Difference between revisions

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 ==Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTP and Sodium==
-<StructureSection load='4tmw' size='340' side='right' caption='[[4tmw]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
+<StructureSection load='4tmw' size='340' side='right'caption='[[4tmw]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4tmw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TMW FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4tmw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TMW FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tmw OCA], [http://pdbe.org/4tmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tmw RCSB], [http://www.ebi.ac.uk/pdbsum/4tmw PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tmw OCA], [https://pdbe.org/4tmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tmw RCSB], [https://www.ebi.ac.uk/pdbsum/4tmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tmw ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/IF2P_CHATD IF2P_CHATD] Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.<ref>PMID:24686316</ref> <ref>PMID:25225612</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 16: / Line 19: @@
 </div>
 <div class="pdbe-citations 4tmw" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Ficner, R]]
+[[Category: Chaetomium thermophilum]]
-[[Category: Kuhle, B]]
+[[Category: Large Structures]]
-[[Category: Gtpase]]
+[[Category: Ficner R]]
-[[Category: Ribosome]]
+[[Category: Kuhle B]]
-[[Category: Subunit joining]]
-[[Category: Translation]]
-[[Category: Translation factor]]