1g1x: Difference between revisions

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-[[Image:1g1x.gif|left|200px]]
- {{Structure
+==STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA==
-|PDB= 1g1x |SIZE=350|CAPTION= <scene name='initialview01'>1g1x</scene>, resolution 2.6&Aring;
+<StructureSection load='1g1x' size='340' side='right'caption='[[1g1x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
+<table><tr><td colspan='2'>[[1g1x]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ekc 1ekc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G1X FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g1x OCA], [https://pdbe.org/1g1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g1x RCSB], [https://www.ebi.ac.uk/pdbsum/1g1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g1x ProSAT]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g1x OCA], [http://www.ebi.ac.uk/pdbsum/1g1x PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1g1x RCSB]</span>
+[https://www.uniprot.org/uniprot/RS6_THET8 RS6_THET8] Located on the outer edge of the platform on the body of the 30S subunit.[HAMAP-Rule:MF_00360]
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/1g1x_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g1x ConSurf].
+<div style="clear:both"></div>
-'''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''
+==See Also==
+*[[Ribosomal protein S15|Ribosomal protein S15]]
+*[[Ribosomal protein S18|Ribosomal protein S18]]
-==Overview==
+*[[Ribosomal protein S6|Ribosomal protein S6]]
-The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry 1EKC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
-==Reference==
-Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10753109 10753109]
-[[Category: Protein complex]]
 [[Category: Thermus thermophilus]]
-[[Category: Agalarov, S C.]]
+[[Category: Agalarov SC]]
-[[Category: Funke, P M.]]
+[[Category: Funke PM]]
-[[Category: Prasad, G S.]]
+[[Category: Prasad GS]]
-[[Category: Stout, C D.]]
+[[Category: Stout CD]]
-[[Category: Williamson, J R.]]
+[[Category: Williamson JR]]
-[[Category: ribosomal proteins s15]]
-[[Category: ribosome]]
-[[Category: rna]]
-[[Category: s18]]
-[[Category: s30 ribosomal subunit]]
-[[Category: s6]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:34:54 2008''