5fv8: Difference between revisions
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New page: '''Unreleased structure''' The entry 5fv8 is ON HOLD Authors: Zaccai, N.R., Mason, J.M., Brady, R.L. Description: Structure of cJun-FosW coiled coil complex. [[Category: Unreleased Str... |
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==Structure of cJun-FosW coiled coil complex.== | |||
<StructureSection load='5fv8' size='340' side='right'caption='[[5fv8]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5fv8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FV8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JEF:O-(O-(2-AMINOPROPYL)-O-(2-METHOXYETHYL)POLYPROPYLENE+GLYCOL+500)'>JEF</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fv8 OCA], [https://pdbe.org/5fv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fv8 RCSB], [https://www.ebi.ac.uk/pdbsum/5fv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fv8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/JUN_HUMAN JUN_HUMAN] Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<ref>PMID:10995748</ref> <ref>PMID:17210646</ref> | |||
==See Also== | |||
*[[C-JUN|C-JUN]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Zaccai | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Brady RL]] | |||
[[Category: Mason JM]] | |||
[[Category: Zaccai NR]] | |||
Latest revision as of 16:28, 26 July 2023
Structure of cJun-FosW coiled coil complex.Structure of cJun-FosW coiled coil complex.
Structural highlights
FunctionJUN_HUMAN Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.[1] [2] See AlsoReferences
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