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==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine== | ==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine== | ||
<StructureSection load='3b7p' size='340' side='right' caption='[[3b7p]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3b7p' size='340' side='right'caption='[[3b7p]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3b7p]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3b7p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B7P FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b7p OCA], [https://pdbe.org/3b7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b7p RCSB], [https://www.ebi.ac.uk/pdbsum/3b7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b7p ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8II73_PLAF7 Q8II73_PLAF7] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7p_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/3b7p_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 21: | Line 22: | ||
==See Also== | ==See Also== | ||
*[[Spermidine | *[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum 3D7]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Dong | [[Category: Dong A]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Hui | [[Category: Hui R]] | ||
[[Category: Kozieradzki | [[Category: Kozieradzki I]] | ||
[[Category: Lew | [[Category: Lew J]] | ||
[[Category: Plotnikov | [[Category: Plotnikov AN]] | ||
[[Category: Qiu | [[Category: Qiu W]] | ||
[[Category: Ren | [[Category: Ren H]] | ||
[[Category: Schapira M]] | |||
[[Category: Schapira | [[Category: Sundstrom M]] | ||
[[Category: Sundstrom | [[Category: Vedadi M]] | ||
[[Category: Vedadi | [[Category: Wasney G]] | ||
[[Category: Wasney | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Wu H]] | ||
[[Category: Wu | [[Category: Zhao Y]] | ||
[[Category: Zhao | |||
Latest revision as of 15:03, 30 August 2023
Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermineCrystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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