3ik4: Difference between revisions
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==CRYSTAL STRUCTURE OF mandelate racemase/muconate lactonizing protein from Herpetosiphon aurantiacus== | ==CRYSTAL STRUCTURE OF mandelate racemase/muconate lactonizing protein from Herpetosiphon aurantiacus== | ||
<StructureSection load='3ik4' size='340' side='right' caption='[[3ik4]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3ik4' size='340' side='right'caption='[[3ik4]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ik4]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3ik4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Herpetosiphon_aurantiacus_DSM_785 Herpetosiphon aurantiacus DSM 785]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IK4 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ik4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ik4 OCA], [https://pdbe.org/3ik4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ik4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ik4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ik4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/AREP_HERA2 AREP_HERA2] Has epimerase activity with a variety of hydrophobic dipeptides (in vitro). Enzyme activity is highest with L-Phe-L-Tyr, but is still relatively low, suggesting that L-Phe-L-Tyr is not the physiological substrate.<ref>PMID:22392983</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/3ik4_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/3ik4_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
*[[Mandelate racemase|Mandelate racemase]] | *[[Mandelate racemase|Mandelate racemase]] | ||
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Herpetosiphon aurantiacus DSM 785]] | ||
[[Category: Almo | [[Category: Large Structures]] | ||
[[Category: Burley | [[Category: Almo SC]] | ||
[[Category: Dickey | [[Category: Burley SK]] | ||
[[Category: Gerlt | [[Category: Dickey M]] | ||
[[Category: Iizuka | [[Category: Gerlt JA]] | ||
[[Category: Iizuka M]] | |||
[[Category: Patskovsky | [[Category: Patskovsky Y]] | ||
[[Category: Sauder | [[Category: Sauder JM]] | ||
[[Category: Toro | [[Category: Toro R]] | ||